Calculate how many units to draw for your tirzepatide dose. Pre-filled with titration schedule presets from 2.5mg through 15mg.
A commonly referenced tirzepatide titration schedule increases dose every 4 weeks. This approach allows the body to adjust at each concentration level before moving to the next step.
| Weeks | Weekly Dose | mcg | Units (10mg/2mL) |
|---|---|---|---|
| 1 - 4 | 2.5 mg | 2,500 mcg | 50 IU |
| 5 - 8 | 5 mg | 5,000 mcg | 100 IU |
| 9 - 12 | 7.5 mg | 7,500 mcg | 150 IU* |
| 13 - 16 | 10 mg | 10,000 mcg | 200 IU* |
| 17 - 20 | 12.5 mg | 12,500 mcg | 250 IU* |
| 21+ | 15 mg | 15,000 mcg | 300 IU* |
*Doses above 100 IU require more than one syringe or a higher concentration (add less water).
Tirzepatide vials are available in several sizes. Larger vials are more practical for users on higher titration doses where each injection uses more compound per dose.
Tirzepatide activates both GIP and GLP-1 receptors, distinguishing it from single-receptor agonists like semaglutide. This dual mechanism is a key area of ongoing research in metabolic science.
Tirzepatide has a half-life of approximately 5 days, supporting once-weekly subcutaneous administration. Many users choose a consistent day and time each week.
At maintenance doses (10-15mg), the standard 2mL reconstitution may require large injection volumes. Many users reduce bac water to 1mL to increase concentration and keep injection volumes smaller.
Reconstituted tirzepatide is typically stored refrigerated at 2-8 degrees Celsius. Using bacteriostatic water supports multi-use stability for approximately 4-6 weeks.
1 mL = 100 units (IU) on a standard U-100 insulin syringe
For higher doses, reducing bac water volume increases concentration and reduces injection volume
Steady-state concentration is typically reached after 4-5 weekly doses at the same level
Store reconstituted vials refrigerated (2-8°C) and use within 4-6 weeks